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IP Watch: Recent Patents Related to PCR, Nucleic Acid Amplification, and Sample PrepTuesday, July 19, 2011 @ 1:45PMThe Medical University of South Carolina Foundation for Research Development has been awarded US Patent No. 7,981,616, "Enhanced detection of RNA using a panel of truncated gene-specific primers for reverse transcription."

This Week in PLoSMonday, July 18, 2011 @ 10:29AMIn PLoS Computational Biology this week, Marc Marti-Renom at Spain's Centro de Investigación Príncipe Felipe and MIT's Leonid Mirny discuss "bridging the resolution gap for structural determination of genomes " using computational approaches that expand upon existing knowledge of chromatin folding principles.

Unique probiotic strains trigger very different immune responses: ResearchersMonday, July 18, 2011 @ 10:10AMThey used a series of immune markers such as T-cell counts in testing a range of strains supplied by Winclove BioIndustries and found immune modulation greatly differed among the selected probiotic types.

Ketamine and Major Depressive Disorder: Is It Better with Special K?Saturday, July 16, 2011 @ 2:33PMMost people have heard of ketamine. [More]

Precision gene targeting in stem cells corrects disease-causing mutationsSaturday, July 16, 2011 @ 1:21PMUsing two distinct methods, researchers have successfully and consistently manipulated targeted genes in both human embryonic stem cells and induced pluripotent stem cells (adult cells that have been reprogrammed to an embryonic stem cell-like state). In one case, scientists employed proteins known as zinc finger nucleases to change a single base pair in the genome, allowing them either to ...

Ready, go! Super Elongation Complex pinpointed as a major regulator in coordinated expression of early developmental ...Saturday, July 16, 2011 @ 12:20PMJust like orchestra musicians waiting for their cue, RNA polymerase II molecules are poised at the start site of many developmentally controlled genes, waiting for the "Go!" signal to read their part of the genomic symphony. An assembly of transcription elongation factors known as Super Elongation Complex, or SEC for short, helps paused RNA polymerases to come online and start transcribing the ...

Sinus Pro Conducting New Research on Fas-L Protein and its Role in Nasal PolypsSaturday, July 16, 2011 @ 1:22AMNasal Polyps will be a thing of the past with expected outcome of research... New York, NY (PRWEB) July 15, 2011 Sinus-Pro has been investigating nasal polyps extensively. The Sinus-Pro team is determined to prove that homeopathy can affect the expression of the Fas-L protein. Research has been done to illustrate the role of a specific protein in the development of nasal polyps. This research ...

New DNA sequencer will provide deeper insight into gene regulationSaturday, July 16, 2011 @ 12:15AMThe Berlin Institute for Medical Systems Biology (BIMSB) of the Max Delbr-ck Center for Molecular Medicine (MDC) in Berlin, Germany, will be the first academic research institution in Continental Europe to acquire a novel DNA sequencer enabling the sequencing of single DNA molecules in real time.

The Unfolding 'SAGA' Of Transcriptional Co-ActivatorsFriday, July 15, 2011 @ 4:20PMSuccessful gene expression requires the concerted action of a host of regulatory factors. Long overshadowed by bonafide transcription factors, coactivators—the hanger-ons that facilitate transcription by docking onto transcription factors or modifying chromatin—have recently come to the fore. In their latest study, published in the July 15, 2011, issue of Genes & Development, researchers at the ...