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  • Ready, Go! Thursday, July 14, 2011 @ 4:44PMStowers researchers pinpoint the Super Elongation Complex as a major regulator in the coordinated expression of early developmental genes.
  • This Week in Nature Thursday, July 14, 2011 @ 10:44AMBy applying a statistical model to seven complete human genome sequences, the Wellcome Trust Sanger Institute's Heng Li and Richard Durbin have generated a " detailed history of human population sizes between approximately ten thousand and a million years ago," which they present in a paper published online in advance in Nature this week.
  • Project Achilles Pinpoints Vulnerabilities in Ovarian Cancer Monday, July 11, 2011 @ 2:33PMIn their largest and most comprehensive effort to date, researchers from the Broad Institute of MIT and Harvard and the Dana-Farber Cancer Institute examined cells from over 100 tumors, including 25 ovarian cancer tumors, to unearth the genes upon which cancers depend. One of these genes, PAX8, is altered in a significant fraction of ovarian tumors -- nearly one-fifth of those surveyed in the ...
  • Genome-scale study of 100 cell lines pinpoints vulnerabilities in ovarian cancer Monday, July 11, 2011 @ 2:07PMCancer is not invincible but its weaknesses can be difficult to detect. An effort known as Project Achilles — named after the Greek warrior whose one vulnerability led to his undoing — was launched to develop a systematic way of pinpointing these weak spots. In their largest and most comprehensive effort to date, researchers from the Broad Institute of MIT and Harvard and the Dana-Farber Cancer ...
  • A first for Oak Creek Wednesday, June 22, 2011 @ 12:34AMTwo women earn college credit certificates
  • LA/hypnosis combination during surgery can aid healing process, reduce drug use and hospital stay time Monday, June 13, 2011 @ 1:05AMUsing a combination of hypnosis and local anaesthesia (LA) for certain types of surgery can aid the healing process and reduce drug use and time spent in hospital, anaesthesiologists have found. The combination could also help avoid cancer recurrence and metastases, according to new research to be presented today at the European Anaesthesiology Congress in Amsterdam.
  • Master Gene May Shed New Light On Lysosomal And Neurodegenerative Disorders Sunday, May 29, 2011 @ 5:31AMCells, like ordinary households, produce "garbage" - debris and dysfunctional elements - that need disposal. When the mechanism for taking out this garbage fails, rare genetic diseases called lysosomal storage disorders (including Tay-Sachs, Batten and Fabry disease) can disable and even kill the children they affect. In adults, such failure leads to neurodegenerative diseases that occur later ...
  • How retinas develop: Scientists make strides in vision research Friday, May 20, 2011 @ 4:26PMNew research is contributing to the basic biological understanding of how retinas develop. In two new studies, scientists document how they used mice as a research model organism to show that the size of different populations of retinal neurons display wide-ranging variability among individuals.
  • :: 18, May 2011 :: SCIENTISTS DISCOVER SWITCH TO SPEED UP STEM CELL PRODUCTION TO FACILITATE DEVELOPMENT OF TREATMENTS ... Tuesday, May 17, 2011 @ 9:27PMA team of scientists from Genome Institute of Singapore (GIS) of the Agency for Science, Technology and Research (A*STAR) have shown how proteins involved in controlling genes work together to carry out their functions in stem cells and demonstrated for the very first time, how they can change interaction partners to make other types of cells.
  • This Week in Nature Thursday, May 12, 2011 @ 12:20PMIn a paper published online in advance in Nature this week, a team led by investigators at the University of Exeter reports on a new fungal clade, which they've named "cryptomycota in anticipation of formal classification."
  • Reportlinker Adds The Global Market for AIDS/HIV Testing and Treatment Thursday, May 12, 2011 @ 4:01AMReportlinker.com announces that a new market research report is available in its catalogue:
  • UT Southwestern Researcher Maps Far-Reaching Effects Of Estrogen Signaling In Breast Cancer Cells Thursday, May 5, 2011 @ 11:17PMA UT Southwestern Medical Center researcher has identified the most comprehensive measurement to date of estrogen's effect on breast cancer cells, showing for the first time how immediate and extensive the effect is. The findings, published online today and in the May 13 print edition of the journal Cell, could lead to a new set of therapeutic applications and provide a model for understanding ...
  • Far-reaching effects of estrogen signaling mapped in breast cancer cells Thursday, May 5, 2011 @ 1:30PMResearchers have made the most comprehensive measurement to date of estrogen's effect on breast cancer cells, showing for the first time how immediate and extensive the effect is.
  • Mutation provides new insight into the molecular mechanisms of aging Thursday, May 5, 2011 @ 1:30PMA new study identifies the mutation that underlies a rare, inherited accelerated-aging disease and provides key insight into normal human aging. The research highlights the importance of a cellular structure called the "nuclear envelope" in the process of aging.
  • What decides neural stem cell fate? Only cells expressing SOX2 gatekeeper gene have potential to become neurons Thursday, May 5, 2011 @ 1:29PMResearchers have found that expression of a gene called SOX2 maintains the potential for neural crest stem cells to become neurons in the peripheral nervous system. Their results could help better inform therapies aimed at neurocristopathies, diseases caused by defects in the neural crest.
  • JCI online early table of contents: May 2, 2011 Monday, May 2, 2011 @ 11:14AM( Journal of Clinical Investigation ) This release contains summaries, links to PDFs, and contact information for the following newsworthy papers to be published online, May 2, 2011, in the JCI: "Skin sensitivity to food allergens explained;" "Cells derived from different stem cells: same or different?;" "A TIF(f)1 between blood cell progenitors leads to leukemia;" "Characterizing key defenders ...
  • Study Suggests That Successful Blueprints Are Recycled by Evolution Monday, May 2, 2011 @ 10:31AMA study by researchers in Austria and the US finds evidence that the different cell types that make up organs have arisen only once during the course of evolution. The programs to develop these cells have been passed on ever since. The study which is published online by Nature Genetics has been supported by the GEN-AU Programme of the Austrian Ministry for Science and Research.
  • Sharing for caring Saturday, April 9, 2011 @ 1:16AMSt. Mary-Corwin and Parkview medical centers are among the first hospitals statewide to get on board with exchanging electronic medical information with other providers through the Colorado Regional Health Information Organization.
  • Movers & Shakers Friday, April 8, 2011 @ 5:20PMCaris Life Sciences announced this week it has hired Richard Bender as senior vice president of medical affairs for oncology.
  • Biologists Pinpoint A Genetic Change That Helps Tumors Move To Other Parts Of The Body Thursday, April 7, 2011 @ 3:24AMMIT cancer biologists have identified a genetic change that makes lung tumors more likely to spread to other parts of the body. The findings, to be published in the April 6 online issue of Nature, offers new insight into how lung cancers metastasize and could help identify drug targets to combat metastatic tumors, which account for 90 percent of cancer deaths. The researchers, led by Tyler Jacks ...
  • OncoGenex, Teva's custirsen preclinical data in CRPC presented at AACR meeting Thursday, April 7, 2011 @ 2:38AMTeva Pharmaceutical Industries Ltd. and OncoGenex Pharmaceuticals, Inc. announced today that new preclinical data of their investigational compound custirsen in castrate resistant prostate cancer were presented this week at the 102nd Annual Meeting of the AACR.
  • Genetic change that helps tumors move to other parts of the body identified Wednesday, April 6, 2011 @ 1:11PMCancer biologists have identified a genetic change that makes lung tumors more likely to spread to other parts of the body. The findings offer new insight into how lung cancers metastasize and could help identify drug targets to combat metastatic tumors, which account for 90 percent of cancer deaths.
  • Biologists pinpoint a genetic change that helps tumors move to other parts of the body Wednesday, April 6, 2011 @ 12:20PMMIT cancer biologists have identified a genetic change that makes lung tumors more likely to spread to other parts of the body. The findings, to be published in the April 6 online issue of Nature, offers new insight into how lung cancers metastasize and could help identify drug targets to combat metastatic tumors, which account for 90 percent of cancer deaths.
  • Maternal diet linked to offspring health: Rat study Sunday, March 20, 2011 @ 11:25AMA poor diet during pregnancy may negatively affect the long term health of offspring by altering genetic factors linked to diabetes, according to new research in rats.
  • Psoriasis Medication Rises Hope In The Fight Against Multiple Sclerosis Tuesday, March 8, 2011 @ 4:23AMFumaric acid salts have been in use against severe psoriasis for a long time. About ten years ago, researchers in Bochum speculated that they may also have a favourable effect on Multiple Sclerosis (MS) as a result of their TH2 polarizing mechanisms. In parallel to phase III studies, research is actively searching for the precise effective mechanisms. This has now been achieved by a ...
  • Fumaric acid salts may protect against Multiple Sclerosis Tuesday, March 8, 2011 @ 3:38AMFumaric acid salts have been in use against severe psoriasis for a long time. About ten years ago, researchers in Bochum speculated that they may also have a favourable effect on Multiple Sclerosis as a result of their TH2 polarizing mechanisms.
  • Key mechanism of childhood respiratory disease identified Monday, March 7, 2011 @ 4:55PMResearchers have identified a critical part of the process by which one of the world's most common and dangerous early childhood infections, respiratory syncytial virus, causes disease.
  • Money Matters – National Consumer Protection Week: Phishing Scams Monday, March 7, 2011 @ 3:32PMThis is National Consumers Protection Week.
  • Psoriasis medication rises hope in the fight against multiple sclerosis Monday, March 7, 2011 @ 12:04PMFumaric acid salts have been in use against severe psoriasis for a long time. About ten years ago, researchers in Bochum speculated that they may also have a favourable effect on Multiple Sclerosis (MS) as a result of their TH2 polarizing mechanisms. In parallel to phase III studies, research is actively searching for the precise effective mechanisms. This has now been achieved by a ...
  • Psoriasis medication rises hope in the fight against multiple sclerosis Monday, March 7, 2011 @ 10:25AMFumaric acid salts have been in use against severe psoriasis for a long time. About ten years ago, researchers speculated that they may also have a favorable effect on multiple sclerosis (MS) as a result of their TH2 polarizing mechanisms. A study with 1,200 MS patients and the fumaric acid salt BG12 has just been completed. Evaluation is expected for summer 2011.
  • Tracing The Possible Role Of Damaged DNA In The Development Of Tumors Monday, March 7, 2011 @ 5:34AMDNA provides the instruction manual for all life forms. Occasionally, instructions are not carried out properly, and bad messages are sent leading to the creation of mutant proteins and possible tumor development...
  • This Week in Nature Thursday, February 24, 2011 @ 10:07AMCold Spring Harbor Laboratory's Jonathan Sebat and his colleagues report in a Nature paper published online in advance that copy-number gains at 7q36.3 are significantly associated with schizophrenia risk.
  • How to Fight a Bogus Bill Friday, February 18, 2011 @ 10:10PMA growing number of health-care charges are outright wrongand left untended, they could wreck your credit score. Here's how to fight back.
  • SpeakWrite LLC Written Transcripts from All Texas Legislative Hearing Committees Now Available Tuesday, February 15, 2011 @ 2:42PMAUSTIN, Texas--(BUSINESS WIRE)--SpeakWrite LLC, an Austin-based offsite transcription company, has begun providing inexpensive full text, verbatim transcripts of all Texas Legislative Hearings, available 24/7.
  • SpeakWrite LLC Written Transcripts from All Texas Legislative Hearing Committees Now Available Tuesday, February 15, 2011 @ 2:31PMSpeakWrite LLC, an Austin-based offsite transcription company , has begun providing inexpensive full text, verbatim transcripts of all Texas Legislative Hearings, available 24/7, with the written transcript delivered via email 24 hours after order.
  • Study That Sheds Light On RNA 'On/Off Switches' May Have Implications For Designing New Antibiotics Monday, February 14, 2011 @ 8:35AMScientists from The Scripps Research Institute have shed new light on a molecular switch that turns genes on or off in response to a cell's energy needs. The study - published February 13, 2011 in an Advance Online Publication of the journal Nature Structural and Molecular Biology - shows these recently discovered RNA "riboswitches" are capable of more complex functions than originally thought ...
  • New round of Triton Research Opportunity (TRO) grants Thursday, February 10, 2011 @ 12:16PMSAN DIEGO — The San Diego Supercomputer Center (SDSC) at the University of California San Diego has announced the latest round of computer allocations under the Triton Research Opportunities (TRO) program associated with the center’s Triton Resource , a data-intensive computing system primarily designed to support UC San Diego and UC researchers.
  • In tiny fruit flies, researchers identify metabolic 'switch' that links normal growth to cancer Wednesday, February 2, 2011 @ 3:23PMUntil now, researchers have known nothing about the metabolic state that occurs when cells divide during early development. Human genetics researchers show in a new study that this cell division in Drosophila depends on a metabolic state much like when cells run amok to form cancerous tumors.
  • Metabolic 'Switch' Identified That Links Normal Growth To Cancer In Drosophila Wednesday, February 2, 2011 @ 9:25AMAs day-old embryos, fruit flies called Drosophila enter a stage in which their cells freely divide and proliferate as the insect grows dramatically in size. This is true for all animals, which undergo most of their growth prior to sexual maturation. Until now, researchers have known nothing about the metabolic state that occurs when cells divide during early development. But in a study published ...
  • In tiny fruit flies, researchers identify metabolic 'switch' that links normal growth to cancer Tuesday, February 1, 2011 @ 11:53AMAs day-old embryos, fruit flies called Drosophila enter a stage in which their cells freely divide and proliferate as the insect grows dramatically in size.
  • Genetic clues to compulsive, self-injurious behavior in rare childhood disorder Monday, January 31, 2011 @ 7:23AMResearch provides new clues for the compulsive behavior and cognitive defects associated with a rare childhood neurological disease called Lesch-Nyhan Disease (LND). Two pathways found to be defective in LND are known to be associated with other neurodegenerative disease, such as Alzheimer's and Parknson's diseases, suggesting common causes of cognitive and behavioral defects in these ...
  • Cellzome: Landmark Study Demonstrates That 'Complexes Matter' In How Epigenetic Inhibitors Interact With Their Drug ... Tuesday, January 25, 2011 @ 5:45AMResults of the first ever chemoproteomic study of inhibition of HDAC (Histone Deacetylase) complexes published today in Nature Biotechnology (Bantscheff et al. Advanced online Publication, DOI: 10.1038/nbt.1759) opens up the potential for a new way of studying potency and selectivity for inhibitors of epigenetic drug targets, such as HDACs. In the study, scientists from Cellzome have ...
  • Acetylation complex fits like a halo over a histone Friday, January 21, 2011 @ 8:29AMTo understand the emerging science of epigenetics-a field that describes how genes may be regulated without altering the underlying DNA itself-scientists are deciphering the many ways in which enzymes act on the proteins surrounding DNA within cells.
  • Genome Viewed As It Turns On And Off Inside Cells Friday, January 21, 2011 @ 5:35AMUCSF researchers have developed a new approach to decoding the vast information embedded in an organism's genome, while shedding light on exactly how cells interpret their genetic material to create RNA messages and launch new processes in the cell. By combining biochemical techniques with new, fast DNA-sequencing technology and advanced computer technology, the team was able to examine with ...
  • Global View Of Blood Cell Development Reveals New And Complex Circuitry Thursday, January 20, 2011 @ 10:18PMResearchers take a systematic approach to catalog factors that control blood cell development A small pool of stem cells replenishes the human body with about 200 billion new blood cells daily. But the elaborate circuitry that determines if a cell will develop into a T cell, red blood cell, or one of the nine or more other blood cell types remains largely unknown. A research team led by ...
  • Team views genome as it turns on, off inside cells Wednesday, January 19, 2011 @ 1:16PMSAN FRANCISCO — UC San Francisco researchers have developed a new approach to decoding the vast information embedded in an organism’s genome, while shedding light on exactly how cells interpret their genetic material to create RNA messages and launch new processes in the cell.
  • UCSF team views genome as it turns on and off inside cells Wednesday, January 19, 2011 @ 12:18PMUCSF researchers have developed a new approach to decoding the vast information embedded in an organism's genome, while shedding light on exactly how cells interpret their genetic material to create RNA messages and launch new processes in the cell.
  • Atlas Of An Organism Wednesday, January 19, 2011 @ 8:19AMWhile every cell of an organism contains the same genes only a proportion are expressed in any tissue at a given stage in development. Knowing the extent of gene transcription is valuable and a team of European researchers has generated an atlas of gene expression for the developing mouse embryo. This will be a powerful resource to determine co-expression of genes and to identify functional ...
  • The Most Detailed Annotation Yet Of The Fruit-Fly Genome Points The Way To Understanding The Genomes Of All Organisms Sunday, January 2, 2011 @ 5:31AMIn the past decade researchers have made astonishing progress in the rapid and accurate sequencing of genomes from all realms of life. Yet the listing of chemical base pairs has gotten far ahead of understanding how the information they contain becomes functional. Even the best-understood genomes conceal mysteries. Genetic information carried by DNA and RNA operates together with the patterns ...
  • More detailed mapping of the fruit fly genome Wednesday, December 22, 2010 @ 4:45PMLBNL and UC Berkeley researchers have gone beyond the mere genetic sequence of the fruit fly to reveal the RNA and chromatin structures that tell us how cells work. The new analysis of the fruit fly and roundworm genomes was performed by the modENCODE team.