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  • IP Watch: Recent Patents Related to PCR, Nucleic Acid Amplification, and Sample Prep Tuesday, July 19, 2011 @ 1:45PMThe Medical University of South Carolina Foundation for Research Development has been awarded US Patent No. 7,981,616, "Enhanced detection of RNA using a panel of truncated gene-specific primers for reverse transcription."
  • This Week in PLoS Monday, July 18, 2011 @ 10:29AMIn PLoS Computational Biology this week, Marc Marti-Renom at Spain's Centro de Investigación Príncipe Felipe and MIT's Leonid Mirny discuss "bridging the resolution gap for structural determination of genomes " using computational approaches that expand upon existing knowledge of chromatin folding principles.
  • Unique probiotic strains trigger very different immune responses: Researchers Monday, July 18, 2011 @ 10:10AMThey used a series of immune markers such as T-cell counts in testing a range of strains supplied by Winclove BioIndustries and found immune modulation greatly differed among the selected probiotic types.
  • Ketamine and Major Depressive Disorder: Is It Better with Special K? Saturday, July 16, 2011 @ 2:33PMMost people have heard of ketamine. [More]
  • Precision gene targeting in stem cells corrects disease-causing mutations Saturday, July 16, 2011 @ 1:21PMUsing two distinct methods, researchers have successfully and consistently manipulated targeted genes in both human embryonic stem cells and induced pluripotent stem cells (adult cells that have been reprogrammed to an embryonic stem cell-like state). In one case, scientists employed proteins known as zinc finger nucleases to change a single base pair in the genome, allowing them either to ...
  • Ready, go! Super Elongation Complex pinpointed as a major regulator in coordinated expression of early developmental ... Saturday, July 16, 2011 @ 12:20PMJust like orchestra musicians waiting for their cue, RNA polymerase II molecules are poised at the start site of many developmentally controlled genes, waiting for the "Go!" signal to read their part of the genomic symphony. An assembly of transcription elongation factors known as Super Elongation Complex, or SEC for short, helps paused RNA polymerases to come online and start transcribing the ...
  • Sinus Pro Conducting New Research on Fas-L Protein and its Role in Nasal Polyps Saturday, July 16, 2011 @ 1:22AMNasal Polyps will be a thing of the past with expected outcome of research... New York, NY (PRWEB) July 15, 2011 Sinus-Pro has been investigating nasal polyps extensively. The Sinus-Pro team is determined to prove that homeopathy can affect the expression of the Fas-L protein. Research has been done to illustrate the role of a specific protein in the development of nasal polyps. This research ...
  • New DNA sequencer will provide deeper insight into gene regulation Saturday, July 16, 2011 @ 12:15AMThe Berlin Institute for Medical Systems Biology (BIMSB) of the Max Delbr-ck Center for Molecular Medicine (MDC) in Berlin, Germany, will be the first academic research institution in Continental Europe to acquire a novel DNA sequencer enabling the sequencing of single DNA molecules in real time.
  • The Unfolding 'SAGA' Of Transcriptional Co-Activators Friday, July 15, 2011 @ 4:20PMSuccessful gene expression requires the concerted action of a host of regulatory factors. Long overshadowed by bonafide transcription factors, coactivators—the hanger-ons that facilitate transcription by docking onto transcription factors or modifying chromatin—have recently come to the fore. In their latest study, published in the July 15, 2011, issue of Genes & Development, researchers at the ...
  • Precision Gene Targeting in Stem Cells Corrects Disease-Causing Mutations Friday, July 15, 2011 @ 8:30AMUsing two methods, Whitehead researchers have manipulated targeted genes in both human embryonic stem (ES) cells and induced pluripotent stem (iPS) cells. In one case, scientists employed proteins known as ZFNs to change a single base pair in the genome, allowing them either to insert or remove mutations known to cause early-onset Parkinson's disease (PD).
  • Sentinel Principle(R) Used to Discover Blood Based Biomarkers to Predict Risk of Liver Cancer from Patients With ... Friday, July 15, 2011 @ 7:12AMTORONTO, ONTARIO--(Marketwire - 07/15/11) - GeneNews Limited (TSX: GEN - News ), a company focused on developing blood-based biomarker tests for the early detection of diseases and personalized health management, announced that a poster entitled "Biomarkers to predict risk of subsequent hepatocellular cancer in patients with chronic hepatitis" describing the initial phase of analysis of its 1 ...
  • Whitehead researchers fix mutated stem cells Thursday, July 14, 2011 @ 12:37PMThe Whitehead Institute at MIT has moved personalized medicine and gene therapy forward with the announcement of a technique that can correct disease-causing mutations in stem cells.
  • Voicebrook to Exhibit at the Association of Pathology Chairs 2011 Annual Meeting Thursday, July 14, 2011 @ 2:05AMVoicebrook to demonstrate alternative speech recognition workflows for Pathology laboratory reporting. [PR.com]
  • Business news briefs Thursday, July 14, 2011 @ 1:04AMSquirrel Hill-based speech recognition firm MModal and its advanced Speech Understanding technology has agreed to be acquired in a $130 million deal. MedQuist Holdings, a medical transcription services company in Franklin, Tenn., will fund the deal with $77.2 million in cash and 4.1 million shares of Medquist stock valued at $52.8 million.
  • MicroRNAs Transform Adult Cells into Neurons Wednesday, July 13, 2011 @ 4:20PMSmall bits of RNA called microRNAs, which can influence the way a cell’s genes are turned on and off, can single-handedly cause a connective tissue cell from human skin to transform into a nerve cell, new research shows.
  • This Week in Nucleic Acids Research Wednesday, July 13, 2011 @ 10:44AMResearchers at the University of California, San Diego, discuss in a Nucleic Acids Research paper published online in advance this week the Saccharomyces cerevisiae gene SUS1 and, in particular, how its splicing pattern changes in response to environmental stimuli.
  • M*Modal acquired for $130 million Wednesday, July 13, 2011 @ 9:48AMSquirrel Hill-based speech recognition firm M*Modal and its advanced Speech Understanding technology have been acquired through a deal worth a total of $130 million by MedQuist Holdings, a medical transcription services company in Franklin, Tenn.
  • Sidra Medical and Research Center to Work With Cerner to Digitize Health Care in Qatar Wednesday, July 13, 2011 @ 4:40AMSidra Medical and Research Center (Sidra) and Cerner have come together to build one of the most technologically advanced health care facilities in the Middle East. Working with Cerner, Sidra will become the first hospital in Qatar, and one of very few in the Middle East, to have a fully integrated clinical information system, based on a foundation of international best practices and regulatory ...
  • MedQuist buys speech recognition company Wednesday, July 13, 2011 @ 1:52AMFranklin-based MedQuist Holdings announced a new chairman and chief executive on Monday along with an agreement to acquire a vendor of speech recognition technology for $130 million.
  • Qatar- Sidra to be first fully digitised hospital in Doha Wednesday, July 13, 2011 @ 12:50AMQatar- Sidra to be first fully digitised hospital in Doha
  • New Product Watch Tuesday, July 12, 2011 @ 5:44PMAffymetrix this week began shipping its Gene Profiling Reagents . Affy also announced the availability of its Gene Profiling Array cGMP U133 P2 , a version of its Human Genome U133 Plus 2.0 Array.
  • Sidra medical centre to have hi-tech clinical info system Tuesday, July 12, 2011 @ 4:57PMSidra Medical and Research Centre will soon become the first hospital in Qatar, and one of very few in the Middle East, to have a fully integrated clinical information system based on a foundation of international best practices and regulatory compliance support.
  • Kristen Saponaro Appointed Vice President of Marketing Tuesday, July 12, 2011 @ 7:49AMWAYNE, Pa. and ALPHARETTA, Ga. -- Precyse, a leader in health information management (HIM) services ...
  • Seasoned Healthcare Communications Professional Joins Precyse Executive Leadership Team Tuesday, July 12, 2011 @ 7:00AMPrecyse, a leader in health information management services and technologies, has announced that Kristen Saponaro has joined the organization's executive leadership team as Vice President of Marketing.
  • Project Achilles pinpoints vulnerabilities in ovarian cancer; Genome-scale study of 100 cell lines reveals cancers ... Tuesday, July 12, 2011 @ 1:26AMCancer is not invincible but its weaknesses can be difficult to detect. Project Achilles was launched to develop a systematic way of pinpointing these weak spots. Researchers examined cells from over 100 tumors, including 25 ovarian cancer tumors, to unearth the genes upon which cancers depend. One of these genes, PAX8, is altered in a significant fraction of ovarian tumors.
  • MedQuist names new CEO and chairman Monday, July 11, 2011 @ 6:24PMMedical transcription company MedQuist Holdings Inc. said Monday it named Roger Davenport to the positions of chairman and CEO, assuming roles previously held by two people.
  • Researchers Describe Gene Activity in Living Cells Monday, July 11, 2011 @ 6:42AMWEDNESDAY, April 27 (HealthDay News) -- Researchers in New York City say they are the first to observe the activity of a single gene in living cells.
  • Sangamo BioSciences Appoints Dr. Geoffrey Nichol as Executive Vice President, Research and Development Monday, July 11, 2011 @ 6:00AMSangamo BioSciences, Inc. today announced the appointment of Geoffrey M. Nichol, B.Med.Sc., M.B., Ch.B., M.B.A., as Executive Vice President, Research and Development effective immediately. Â In this newly created position, Dr.
  • Digirad Names Armando Jackson Senior Vice President of Product Sales Monday, July 11, 2011 @ 5:06AMWill Lead Sales Team Initiatives in Hospital Market, Product Expansion, Diversification of Commercial Base
  • Ruben Rosario: Group that reaches out to parents who have lost children to hold conference in Minneapolis Monday, July 11, 2011 @ 12:06AMJoannie Kemling can't bear to listen to Neil Diamond. Cathy Seehuetter hasn't celebrated her birthday in 16 years.
  • Control of gene expression: Mediator MED26 shifts an idling polymerase into high gear Thursday, July 7, 2011 @ 1:18PMScientists have identified a switch that allows RNA polymerase to shift gears from neutral into drive and start transcribing. This work sheds light on a process fundamental to all plant or animal cells and suggests how transcriptional anomalies could give rise to tumors.
  • Study suggests new strategy to prevent infertility, birth defects Thursday, July 7, 2011 @ 10:15AMA strategy that has been shown to reduce age-related health problems in several animal studies may also combat a major cause of age-associated infertility and birth defects. Investigators from Massachusetts General Hospital have shown that restricting the caloric intake of adult female mice prevents a spectrum of abnormalities, such as extra or missing copies of chromosomes, that arise more ...
  • Aventura Hospital and Medical Center Selects ProVation Medical Software for Procedure Documentation and Coding Thursday, July 7, 2011 @ 8:22AMMINNEAPOLIS--(BUSINESS WIRE)--Wolters Kluwer Health, a leading global provider of information for healthcare professionals and students, announced today that Aventura Hospital and Medical Center has selected its ProVation® MD software for gastroenterology (GI) procedure documentation and coding. ProVation MD replaces dictation and transcription and allows physicians to efficiently document ...
  • Control of Gene Expression: Mediator MED26 Shifts an Idling Polymerase Into High Gear Wednesday, July 6, 2011 @ 11:41PMA report from the Conaway lab at the Stowers Institute for Medical Research in the July 8, 2011, edition of the journal Cell identifies a switch that allows RNA polymerase to shift gears from neutral into drive and start transcribing. This work sheds light on a process fundamental to all plant or animal cells and suggests how transcriptional anomalies could give rise to tumors.
  • Baby's death spotlights risks linked to computerized hospital systems Wednesday, July 6, 2011 @ 9:51PMData mix-up leads to infant's death.
  • 'Detox protein' is collaborator in pancreatic and lung cancer development Wednesday, July 6, 2011 @ 3:02PM(Medical Xpress) -- UK scientists have revealed that a ‘detox’ protein which mops up harmful 'reactive oxygen' in cells could also trigger pancreatic and lung cancer development, according to a study published in Nature, today.
  • Roosevelt's Schaumburg campus opens college of pharmacy Wednesday, July 6, 2011 @ 1:05PMDiane Cluxton is turning to higher education for something it's no longer as known for as it once was - the promise of employment and a good salary upon graduation.
  • Transcription factor is potential target for liver cancer treatment Wednesday, July 6, 2011 @ 11:34AMAltering the body's metabolism could be an effective treatment for deadly liver cancer, researchers report. The finding that inhibiting heat shock transcription factor 1, or HSF1, prevents liver cancer in mice also is another wake-up call that a low-fat, healthy diet is an effective cancer deterrent. HSF1 and its target genes are important to metabolism regulation.
  • What causes brain cancer? Understanding glioblastoma at the genetic, molecular level Wednesday, July 6, 2011 @ 11:33AMGlioblastoma is the most common and most lethal form of brain tumor in people. New research offers a novel way to determine what biological functions go awry when the tumor first begins to form. Understanding the problems at the molecular level might one day reveal the underlying mechanism of carcinogenesis in glioblastoma and ultimately lead to treatments or even preventative measures.
  • Essential Role Of A Molecule In Skeletal Muscle Development Reveals New UEA Study Wednesday, July 6, 2011 @ 8:18AMAccording to a report published this week in the journal Proceedings of the National Academy of Sciences (PNAS), an essential role of a molecule in skeletal muscle development has been discovered by researchers at the University of East Anglia (UEA). The finding of the current study could prove helpful in the future, in curing certain ailments that require muscle regeneration or maintenance of ...
  • Today's obituaries: Paula Vasquez, 54, of Bay City, was a title researcher at Bay Title and Abstract Co. Wednesday, July 6, 2011 @ 7:51AMHere are today's obituaries from The Bay City Times.
  • Stem Cell-Based Gene Therapies Can Deliver Their Promise By Advanced Genetic Tools & Techniques Monday, July 4, 2011 @ 1:19PMGene therapy, a technique for correcting defective genes that are responsible for disease development can be used more effectively by targeting gene delivery and high gene expression levels in bone marrow by the use of advanced genetic tools and techniques. This was recently reported with examples in five engaging articles published in the latest issue of Human Gene Therapy. To select and target ...
  • Protein structure of key molecule in DNA transcription system deciphered Sunday, July 3, 2011 @ 1:18PMScientists have deciphered the structure of an essential part of Mediator, a complex molecular machine that plays a vital role in regulating the transcription of DNA.
  • Sparks College Building gets a “Make Over” Saturday, July 2, 2011 @ 4:21PMMost residents and even the visitors to Shelbyville would agree a huge part of the charm of our city is the old restored houses and buildings.
  • The Bay Area's Star Reporting Service, Inc. Explains the Importance of Court Reporting Saturday, July 2, 2011 @ 2:33AMHaving served the community for more than 30 years, Star Reporting Service, Inc. explains the importance of court reporting services.San Francisco, CA (Vocus/PRWEB) July 02, 2011 Star Reporting Service announces that for more than 30 years, it has provided continuous and personalized services to the legal and private communities of the Bay Area. Family owned and operated, Star Reporting Service ...
  • Growing Fiber Internet in Rural America: A Stimulus Success Story Friday, July 1, 2011 @ 4:27PMIf you think the Obama administration’s stimulus package is about digging ditches, you’d be right — at least when it comes to funding broadband efforts in rural areas.
  • Team Finds Ties Between Open Chromatin Regions and Functionally Important GWAS Variants Friday, July 1, 2011 @ 2:14PMNEW YORK (GenomeWeb News) – A Wellcome Trust Sanger Institute-led team reported in PLoS Genetics last night that it has come up with a strategy for sifting through genome-wide association study data to narrow in on functionally relevant genetic changes.
  • Downloads and Upgrades Friday, July 1, 2011 @ 1:44PMBy purchasing the integrated version of Genome Trax from Strand, Avadis NGS users will have access to Biobase's Transfac, which contains more than 3,000 regulatory sites; HGMD Professional, which includes 80,000 disease-linked mutations; over 600,000 ChIP-seq fragments; post-translational modifications; and transcription start sites.
  • Bar codes reduced medication errors in hospital study Thursday, June 30, 2011 @ 10:20PMYou see them at the checkout counter: black bars on stickers that cashiers scan before ringing up a scale. Bar-coding...
  • New approach to link genome-wide association signals to biological function Thursday, June 30, 2011 @ 6:26PMResearchers have identified a new strategy to improve the outcome of genome-wide association (GWA) studies. This will lead to a better understanding of the function of affected genes and the biological pathways involved, potentially translating these findings into clinical benefits. It is estimated that this approach, which finds the open chromatin regions in human cells, could be used in one in ...